Hepatitis B News and Research

Latest Hepatitis B News and Research

Study finds higher mortality and lower transplant rates among Black patients with cirrhosis

Black patients with cirrhosis - late-stage liver disease - are about 25% more likely to die compared to non-Hispanic white patients and four times less likely to receive a liver transplant, reports a new Northwestern Medicine study.

23 Jun 2021

First spatial scan analysis helps identify hotspots of undervaccinated children

The map of Montana Kayla Irish pulls up is peppered with red circles, each cluster providing details behind one of today's timely topics - childhood vaccination.

23 Jun 2021

University of Louisville receives NIH funding to support research into liver-related illness

The University of Louisville Hepatobiology and Toxicology Center of Biomedical Research Excellence has received $11.3 million in funding from the National Institutes of Health to support its research into liver-related illness for an additional five years.

21 Jun 2021

Viral phosphoesterases (including in CoVs) can restrict antiviral innate immunity

An interesting new study describes the activities of a family of viral enzymes called two-histidine-phosphoesterases (2H-PEs), found in coronaviruses (CoVs) and rotaviruses, as well as a mammalian A-kinase anchoring protein enzyme, AKAP7, that shares the same function. Together called 2’,5’-PEs, these enzymes all break down 2’,5’-oligoadenylate compounds that activate the antiviral enzyme ribonuclease L (RNase L).

21 Jun 2021

Which vitamins and minerals help with COVID?

A study published in the journal Inflammopharmacology reviewed recent data related to the role of vitamins and minerals in treating COVID-19 patients. The primary goal of the review is to highlight the possible therapeutic role of vitamins A, B, C, D, E and K, and micronutrients as immunity boosters in COVID-19 patients.

18 Jun 2021

The role of natural killer cells in fight against viral infections including SARS-CoV-2

In an effort to further understand the role of NK cells in combatting COVID-19, a group of researchers explored NK cells in acute viral infections, citing flavivirus and influenza virus infections as examples.

17 Jun 2021

Novel altruistic stem cell defense mechanism may be targeted to develop new COVID-19 vaccines

The SARS-CoV-2 virus that causes COVID-19 may have the ability to reactivate dormant tuberculosis (TB). In a novel study scientists report in The American Journal of Pathology that infection with a specific coronavirus strain reactivated dormant Mycobacterium tuberculosis (MTB) in mice.

16 Jun 2021

Prior vaccination against diphtheria and tetanus associated with less severe COVID-19

The researchers found that individuals with registered diphtheria or tetanus vaccinations were less likely to develop severe COVID-19 than people who had only received other vaccinations. The results of this study are posted to the medRxiv* preprint server.

16 Jun 2021

Experts call for more programs to help Aboriginal and Torres Strait Islander people with liver cancer

Rising numbers of liver cancer in Aboriginal and Torres Strait Islander communities has led experts at Flinders University to call for more programs, including mobile liver clinics and ultrasound in rural and remote Australia.

15 Jun 2021

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

The Southwest National Primate Research Center at Texas Biomedical Research Institute has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026.

15 Jun 2021

Alkaloids show potential as treatments for COVID-19

To further study these organic compounds, researchers from Kermanshah University of Medical Sciences, Iran, and Universidad de Santiago de Chile, Chile, reviewed the role of alkaloids as a potential antiviral, specifically against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They presented the chemistry, plant sources, and antiviral effects of alkaloids and their anti-SARS-CoV-2 effect.

15 Jun 2021

Plasma zinc status not an effective prognostic factor for hospitalized COVID-19 patients

Due to previous evidence suggesting that zinc deficiencies can lead to complications along with an impaired antiviral response, a group of international researchers has undertaken a prospective observational study to investigate this association further.

14 Jun 2021

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

14 Jun 2021

Role of traditional medicine against SARS-CoV-2

A group of researchers at Kannur University reviewed selected papers and in silico work on potential drug leads that could be used to manage COVID-19.

13 Jun 2021

Humoral innate pattern recognition molecules against SARS-CoV-2

In a paper recently uploaded to the preprint server medRxiv by Garlanda et al. (June 8th, 2021), humoral pattern recognition molecules are explored for affinity towards SARS-CoV-2, contributing to unraveling the role of these molecules in COVID-19 disease progression.

13 Jun 2021

New open-source tool designed to predict drug overdose mortality in the U.S.

For two decades, the number of Americans who die each year from drug overdoses has steadily risen, from less than 20,000 in 1999 to more than 80,000 in 2020.

10 Jun 2021

Research suggests low platelet counts may be associated with Oxford-AstraZeneca vaccine

A condition that affects the blood, known as idiopathic thrombocytopenic purpura (ITP), may be associated the Oxford-AstraZeneca vaccine in rare cases, research suggests.

9 Jun 2021

Clinical trial investigates effectiveness of delivering HIV, substance use care through mobile clinics

A clinical trial is underway in five U.S. cities to determine whether delivering integrated health services through mobile clinics can improve HIV and substance use outcomes among people with opioid use disorder who inject drugs.

9 Jun 2021

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

In a recent study published in the journal Pathogens, researchers carried out a molecular docking study for 17 structural analogs prepared from natural maslinic and oleanolic acids and screened them against SARS-CoV-2 main protease. They also experimentally validated the data by determining the half-maximal cytotoxic and inhibitory concentrations of each of the 17 compounds. The researchers investigated whether the compound with antiviral activity affected viral adsorption, replication, or viricidal effect using a plaque infectivity reduction assay.

9 Jun 2021

Maternal SARS-CoV-2 infection imprints immune response in the newborn

A new bioRxiv* preprint reports the immunological footprint in the newborn left by maternal infection with SARS-CoV-2 during pregnancy.

4 Jun 2021

Hepatitis B News and Research

Latest Hepatitis B News and Research

Study finds higher mortality and lower transplant rates among Black patients with cirrhosis

First spatial scan analysis helps identify hotspots of undervaccinated children

University of Louisville receives NIH funding to support research into liver-related illness

Viral phosphoesterases (including in CoVs) can restrict antiviral innate immunity

Which vitamins and minerals help with COVID?

The role of natural killer cells in fight against viral infections including SARS-CoV-2

Novel altruistic stem cell defense mechanism may be targeted to develop new COVID-19 vaccines

Prior vaccination against diphtheria and tetanus associated with less severe COVID-19

Experts call for more programs to help Aboriginal and Torres Strait Islander people with liver cancer

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

Alkaloids show potential as treatments for COVID-19

Plasma zinc status not an effective prognostic factor for hospitalized COVID-19 patients

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Role of traditional medicine against SARS-CoV-2

Humoral innate pattern recognition molecules against SARS-CoV-2

New open-source tool designed to predict drug overdose mortality in the U.S.

Research suggests low platelet counts may be associated with Oxford-AstraZeneca vaccine

Clinical trial investigates effectiveness of delivering HIV, substance use care through mobile clinics

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

Maternal SARS-CoV-2 infection imprints immune response in the newborn

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Hepatitis B News and Research

Latest Hepatitis B News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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